Finding a sustainable alternative to cement is crucial to mitigate climate change. This presentation introduces an innovative approach to investigate alkali-activated binders and monitor kinetic reaction using Raman spectroscopy. The dissolution of precursors by alkalis was continuously monitored for 24 hours immediately after mixing, which was found to be especially helpful to optimize the appropriate mixing procedure. Coupled with a new method for predicting the final products of alkali-activated materials using comprehensive phase-analysis, the cost and performances could be better controlled and optimized. Field applications of optimized AAM mixes based on fly ash, slag, or red mud could achieve 1) cement free with more than 80% reduction in carbon footprint, 2) ~25% reduction in cost, 3) cured at ambient temperature with well controlled setting time, flowability and other fresh properties, 4) similar or even superior hardened properties and durability, and 5) mass production ready.